反应详情

6.5 ml of thionyl chloride are added dropwise, at room temperature, with stirring, to 7.5 g of 6,6-difluorohex-5-enoic acid and a drop of dimethylformamide. The mixture is then stirred at reflux temperature for 5 hours, the excess thionyl chloride is evaporated off in a rotary evaporator and the residue is distilled at 86° and 100 mbar. The title product is obtained in the form of a colourless fluid.

1. temperatureat reflux temperature for 5 hours
2. customthe excess thionyl chloride is evaporated off in a rotary evaporator
3. distillationthe residue is distilled at 86°