Hydrochloric Acid → HCID 19082570, compound

HRID 963586Notes

Reaction equation

HRID 963586 reaction equation
[F:1][C:2]([F:24])([F:23])[C:3]([F:22])([CH2:7][CH2:8][C:9]([F:21])([F:20])[C:10]([F:19])([F:18])[C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])[C:4]([O-:6])=[O:5].[Na+].Cl.CCOCC>O>[F:1][C:2]([F:23])([F:24])[C:3]([F:22])([CH2:7][CH2:8][C:9]([F:20])([F:21])[C:10]([F:18])([F:19])[C:11]([F:16])([F:17])[C:12]([F:13])([F:14])[F:15])[C:4]([OH:6])=[O:5]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 23675694HCID 23675694, compound

Product 1

HCID 19082570HCID 19082570, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Sodium 2-trifluoromethyl-2,5,5,6,6,7,7,8,8,8-decafluorooctanoate was dissolved in water with vigorous stirring and 6N aqueous hydrochloric acid was added slowly to adjust the pH of the solution to about 1.0, and then ether was added to extract the product. The organic layer was separated, washed with water, and dried over magnesium sulfate. After removal of the solvent in vacuo, the residue was dried under high vacuum to give quantitative yield of 2-trifluoromethyl-2,5,5,6,6,7,7,8,8,8-decafluorooctanoic acid, formula above, as a white solid having a melting point of 45°-46° C.

Workup

  1. extractionto extract the product
  2. customThe organic layer was separated
  3. washwashed with water
  4. dry with materialdried over magnesium sulfate
  5. customAfter removal of the solvent in vacuo
  6. customthe residue was dried under high vacuum

Sources & evidence

ORD record
ord-c2574a32a4c64736a715873ffe0d67f5
Source dataset
uspto-grants-1998_06
Patent number
US05763552

Reaction notes

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