HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Dihydro-7-(2-mercaptoethyl)-1-pyrindine-6,6-bisphosphonic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dihydro-7-(2-acetylthioethyl)-1-pyrindine-6,6-bisphosphonic acid, tetraethyl ester | HCID 86752760 | — |
| Product | Dihydro-7-(2-mercaptoethyl)-1-pyrindine-6,6-bisphosphonic acid | HCID 86752761 | — |
Reaction Steps
Dihydro-7-(2-acetylthioethyl)-1-pyrindine-6,6-bisphosphonic acid, tetraethyl ester (4.0 mmol) is added to 6N HCl (35 ml) and heated at reflux under nitrogen for 18 hours. The reaction mixture is then cooled and concentrated under reduced pressure. The product is obtained by recrystallizing from water and isopropanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763611 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-1601c17761b34246994f7fce36b6dcf2 |
| Source note | uspto-grants-1998_06 |