反应详情

Dihydro-7-(2-acetylthioethyl)-1-pyrindine-6,6-bisphosphonic acid, tetraethyl ester (4.0 mmol) is added to 6N HCl (35 ml) and heated at reflux under nitrogen for 18 hours. The reaction mixture is then cooled and concentrated under reduced pressure. The product is obtained by recrystallizing from water and isopropanol.

1. temperatureheated
2. temperatureat reflux under nitrogen for 18 hours
3. temperatureThe reaction mixture is then cooled
4. concentrationconcentrated under reduced pressure
5. customThe product is obtained
6. customby recrystallizing from water and isopropanol