HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → 1-(3-Acetoxy-2-fluoroprop-1-enyl)-1-(2,4-difluorophenyl)cyclopropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 1-(2,4-Difluorophenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane | HCID 54231943 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 1-(3-Acetoxy-2-fluoroprop-1-enyl)-1-(2,4-difluorophenyl)cyclopropane | HCID 54249341 | 92% |
Reaction Steps
The method of Example 17 was repeated using acetyl chloride (0.46 ml), 1-(2,4-difluorophenyl)-1-(2-fluoro-3-hydroxyprop-1-enyl)cyclopropane (Example 15) (0.21 g), benzene (12 ml) and pyridine (0.09 ml) to yield the title compound (0.22 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763700 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-9e53db628f1f4e5ba5524be5026ecc66 |
| Source note | uspto-grants-1998_06 |