Phenol → HCID 22117428, compound

HRID 963918Notes

Reaction equation

HRID 963918 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[OH:10])([CH3:3])[CH3:2].Cl[C:12]([CH3:20])([CH2:14][CH2:15][C:16](Cl)([CH3:18])[CH3:17])[CH3:13].C1(O)C=CC=CC=1>>[CH:1]([C:4]1[C:5]([OH:10])=[CH:6][C:7]2[C:12]([CH3:20])([CH3:13])[CH2:14][CH2:15][C:16]([CH3:18])([CH3:17])[C:8]=2[CH:9]=1)([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 996PhenolHCID 69432-IsopropylphenolHCID 80360Hexane, 2,5-dichloro-2,5-dimethyl-

Product 1

HCID 22117428HCID 22117428, compound

Procedure

In a manner similar to Example 7(a) above, by the reaction of 30 g (0.22 mol) of 2-isopropylphenol with 40.3 g (0.22 mol) of 2,5-dichloro-2,5-dimethylhexane, 48.9 g (90%) of the expected phenol of melting point 79°-80° C. were obtained after chromatography on a silica column eluted with a mixture of dichloromethane and hexane (40/60).

Workup

  1. customwere obtained after chromatography on a silica column
  2. washeluted with a mixture of dichloromethane and hexane (40/60)

Sources & evidence

ORD record
ord-017fc04e56f54368898e58b3c088e480
Source dataset
uspto-grants-1998_06
Patent number
US05766610

Reaction notes

Loading…