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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 964018Generated: October 30, 2026

HCID 15379646, compound → 3-CYANOMETHYL-6-ACETYLOXAZOLO[4,5-b]PYRIDIN-2(3H)-ONE

https://huagongshe.com/reaction/964018

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 15379646HCID 15379646—
Reactant6-Bromo-3-methyl[1,3]oxazolo[4,5-b]pyridin-2(3H)-oneHCID 15926016—
Product3-CYANOMETHYL-6-ACETYLOXAZOLO[4,5-b]PYRIDIN-2(3H)-ONEHCID 19079295—

Reaction Steps

The method of operation is the same as that used for the synthesis of the compound of Example 1 (coupling with 1-ethoxy-1-(trimethylstannyl)ethylene). 6-bromo-3-(cyanomethyl)oxazolo[4,5-b]pyridin-2(3H)-one from Preparation 3 is used instead of the 6-bromo-3-methyloxazolo[4,5-b]pyridin-2(3H)-one from Preparation 2. The yield obtained is 60%. ##STR48##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05767128
Source datasetuspto-grants-1998_06
ORD IDord-a01f0868a0fe4eea9d39c856b25f7060
Source noteuspto-grants-1998_06