Diatrizoate → Potassium 3,5-diacetylamino-2,4,6-triiodobenzoate

Participants

Reaction Conditions

Reaction Steps

A suspension of 3,5-diacetylamino-2,4,6-triiodobenzoic acid (0.5 g, 0.81 mmol) in water (5 ml) was heated to 60° C. and an aqueous solution of KOH prepared by dissolving KOH (46 mg, 0.81 mmol) in water (2 ml) was added. A solution of 0.5N KOH was added dropwise to the suspension to adjust it to pH 7. Water was removed under reduced pressure to give a residue which was washed twice with ethanol and dried under reduced pressure.

Provenance & Evidence