反应详情

80 ml of acetone, 9.1 g (0.06 mol) of 1-bromo-3-methyl-2-butene and 8.0 g (0.058 mol) of anhydrous potassium carbonate were added to 8.0 g (0.058 mol) of 2,5-dimethylthiophenol, and the mixture was refluxed under heat for 1 hour. After the completion of the reaction, a formed salt was removed by filtration, and the acetone was distilled off under reduced pressure. Then, ethyl acetate was added to the residue, and the mixture was washed with a saturated sodium chloride aqueous solution. The mixture was dried over anhydrous sodium sulfate, and then the ethyl acetate was distilled off to give 12 g (yield 100%) of 2-methyl-4-(2,5-dimethylphenyl)thio-2-butene.

1. temperaturethe mixture was refluxed
2. temperatureunder heat for 1 hour
3. customAfter the completion of the reaction
4. customa formed salt was removed by filtration
5. distillationthe acetone was distilled off under reduced pressure
6. additionThen, ethyl acetate was added to the residue
7. washthe mixture was washed with a saturated sodium chloride aqueous solution
8. dry with materialThe mixture was dried over anhydrous sodium sulfate
9. distillationthe ethyl acetate was distilled off