Hydrochloric Acid → HCID 19080059, compound

HRID 964417Notes

Reaction equation

HRID 964417 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([O:10]C)=[O:9])[CH:5]=[CH:4][C:3]=1/[CH:12]=[CH:13]/[C:14]1[CH:19]=[CH:18][C:17]([C:20]([O:22]C)=[O:21])=[CH:16][CH:15]=1.[OH-].[Na+].Cl>CO>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([OH:10])=[O:9])[CH:5]=[CH:4][C:3]=1/[CH:12]=[CH:13]/[C:14]1[CH:15]=[CH:16][C:17]([C:20]([OH:22])=[O:21])=[CH:18][CH:19]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 86752814HCID 86752814, compound

Product 1

HCID 19080059HCID 19080059, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A suspension of 3.0 g of dimethyl (E)-2-chloro-stilbene-4,4'-dicarboxylate in 30 ml of methanol was treated with 36 ml of 1M sodium hydroxide solution and heated under reflux for 5 hours. After cooling, 37 ml of 1M hydrochloric acid were added dropwise. The resulting slurry was suction filtered; the residue was washed with water and dried at 70° C. in a vacuum to give (E)-2-chloro-stilbene-4,4'-dicarboxylic acid, MS: m/z 302 (M+).

Workup

  1. temperatureheated
  2. temperatureunder reflux for 5 hours
  3. temperatureAfter cooling
  4. filtrationfiltered
  5. washthe residue was washed with water
  6. customdried at 70° C. in a vacuum

Sources & evidence

ORD record
ord-08f98027d2f04924891df7b72e84823d
Source dataset
uspto-grants-1998_06
Patent number
US05767268

Reaction notes

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