HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 2-Methylquinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 2-Aminobenzophenone | HCID 76080 | — |
| Product | 2-Methylquinazoline | HCID 588987 | — |
Reaction Steps
In this method, 2-aminobenzophenone derivative (IV) is reacted with acetonitrile to yield 2-methylquinazoline derivative (IX), which is then brominated to 2-bromomethylquinazoline derivative (II-4). The reaction of compound (IV) and acetonitrile is carried out in the same manner as method D. Bromination of compound (IX) is carried out in the same manner as the bromination of compound (VII) by method C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05770602 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-e51706796601477f9a062c3250903ba2 |
| Source note | uspto-grants-1998_06 |