反应详情

温度

80 °C

200 gm of succinic anhydride and 800 gm of aluminum chloride were added to 250 ml of 2-fluorotoluene, and the mixture was heated at 80° C. for 1 hour. Upon the addition of 5 l of 1% cold hydrochloric acid aqueous solution, the reaction mixture was extracted with ethyl acetate, washed with 1N hydrochloric acid and water, and dried over anhydrous sodium sulfate. The solvent was evaporated to obtain 345 gm of the title compound.

1. extractionthe reaction mixture was extracted with ethyl acetate
2. washwashed with 1N hydrochloric acid and water
3. dry with materialdried over anhydrous sodium sulfate
4. customThe solvent was evaporated