Ethyl Acrylate → HCID 19074354, compound

HRID 964933Notes

Reaction equation

HRID 964933 reaction equation
[CH2:1]([N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH2:5]1)[CH:2]=[CH2:3].[C:10]([O:14][CH2:15][CH3:16])(=[O:13])[CH:11]=[CH2:12]>C(O)C>[CH2:1]([N:4]1[CH2:9][CH2:8][N:7]([CH2:12][CH2:11][C:10]([O:14][CH2:15][CH3:16])=[O:13])[CH2:6][CH2:5]1)[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 8821Ethyl AcrylateHCID 8064221-Allylpiperazine

Product 1

HCID 19074354HCID 19074354, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 1-(2-propenyl)piperazine (6.6 g) and ethyl 2-propenoate (11.3 ml) in ethanol (100 ml) was stirred and refluxed for 1 hour 30 minutes. The solvent was evaporated, yielding 9.6 g (80%) of ethyl 4-(2-propenyl)- 1-piperazine-propanoate (interm. 1).

Workup

  1. temperaturerefluxed for 1 hour 30 minutes
  2. customThe solvent was evaporated

Sources & evidence

ORD record
ord-369c268154ec4b96bbd6756159752a78
Source dataset
uspto-grants-1998_06
Patent number
US05773433

Reaction notes

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