Hydrochloric Acid → HCID 19076186, compound

Participants

Reaction Steps

A solution of NaOH (0.44 g, 11 mmol) in H2O (12 mL) was added to a suspension of 3amino-7-methoxy-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 6 (1.72 g, 7.34 mmol) in H2O (100 mL) and MeOH (20 mL). After 5 h the resulting solution was neutralized with HCl (1M, 11 mL) and concentrated to give 7 (2.41 g, theoretically containing approx. 33% NaCl by weight). LRMS (ES), [M+H] m/z=221. ##STR34##

Provenance & Evidence