Thymine → HCID 54034076, compound

HRID 965321Notes

Reaction equation

HRID 965321 reaction equation
[CH2:1]([O:3][C:4](=[O:20])[CH:5]([N:17]=[C:18]=[O:19])[CH2:6][CH2:7][CH2:8][NH:9][C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[CH3:2].[NH:21]1[CH:29]=[C:27]([CH3:28])[C:25](=[O:26])[NH:24][C:22]1=[O:23]>>[CH2:1]([O:3][C:4](=[O:20])[CH:5]([NH:17][C:18]([N:21]1[CH:29]=[C:27]([CH3:28])[C:25](=[O:26])[NH:24][C:22]1=[O:23])=[O:19])[CH2:6][CH2:7][CH2:8][NH:9][C:10]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:11])[CH3:2]

Participants

3

Reactant 2

HCID 1135ThymineHCID 54358079HCID 54358079, compound

Product 1

HCID 54034076HCID 54034076, compound

Procedure

The reaction solution from Example 10 is placed in a flask and to this is added thymine (12.6 g, 0.1 mol) . The resulting solution is allowed to stir for 12 hours, then is evaporated to a solid, which is purified by column chromatography using dichlormethane:ethanol as the eluent.

Workup

  1. customis evaporated to a solid, which
  2. customis purified by column chromatography

Sources & evidence

ORD record
ord-97bb628d686c43858b1c82085d00f209
Source dataset
uspto-grants-1998_06
Patent number
US05773571

Reaction notes

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