Formic Acid → HCID 54364803, compound

Participants

Reaction Steps

To a suspension of methyl 2-fluoromethoxyimino-2-(5-amino-1,2,4-thiadiazole-3-yl)-acetate (anti-isomer) (1.17 g, 5 mmol) in formic acid (1.38 g, 30 mmol), acetic anhydride (1.12 g, 10 mmol) was added. The mixture was treated in the same procedure as described in Example 9 to give methyl 2-fluoromethoxyimino-2-(5-formamido-1,2,4-thiadiazole-3-yl)-acetate (syn-isomer) (991 mg, yield: 73.8%).

Provenance & Evidence