HRID965578

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1

HCID7404

Benzenesulfonyl chloride, 4-nitro-

C6H4ClNO4S

反应SMILES：CNC1(c2ccccc2Cl)C(=O)Nc2ccc(Cl)cc21

HCID19076510

未命名化合物

PRODUCTS

产物

反应SMILES：CNC1(c2ccccc2Cl)C(=O)N(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)c2ccc(Cl)cc21

HCID19076581

未命名化合物

收率 68.9%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

This compound is prepared according to the procedure described in EXAMPLE 11 from 7.03 g of 5-chloro-3-(2-chlorophenyl)-1,3-dihydro-3-(methylamino)-indol-2-one and 5.73 g of 4-nitrobenzenesulfonyl chloride. Chromatography on silica using DCM as the eluent gives 7.76 g of the expected product after crystallization from iso ether. M.p.=220°-221° C.

WORKUP

后处理

customThis compound is prepared