反应详情

A mixture of 4-chloro-5,6,7,8-tetrahydroquinazoline-2-ylamine (117 mg, 0.64 mmol), triethylamine (259 mg, 2.56 mmol), dl-leucine ethyl ester hydrochloride (250 mg, 1.28 mmol) and n-butanol (2 ml) was reacted for 6 hours at 80-90° C. According to the post-treatment of Example 1, the object compound was obtained (104.3 mg, 72.1%).

1. customwas reacted for 6 hours at 80-90° C
2. customthe object compound was obtained (104.3 mg, 72.1%)