HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 3-(4-Chloro-phenyl)-7,8-dimethoxy-6-nitro-chromen-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Phosphorodichloridic acid, phenyl ester | HCID 13038 | — |
| Reactant | (4-Chlorophenyl)acetic acid | HCID 15880 | — |
| Reactant | 3,4-Dimethoxy-2-hydroxy-5-nitrobenzaldehyde | HCID 22313432 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 3-(4-Chloro-phenyl)-7,8-dimethoxy-6-nitro-chromen-2-one | HCID 22313449 | — |
Reaction Steps
2-Hydroxy-3,4-dimethoxy-5-nitro-benzaldehyde (2.44 g), 4-chlorophenyl acetic acid (1.82 g), PhOPOCl2 (1.6 ml) and triethylamine (4.5 ml) in 1,2-dichloroethane (125 ml) were refluxed for 5 hours as described in example 1(a). Yield: 2.40 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06951870B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-56a814fa2cdb411599e2f52519d0c7e9 |
| Source note | uspto-grants-2005_10 |