Morpholine, 4-(chloroacetyl)- → 5-AMINO-6-CHLORO-2-ETHYL-N-{[1-(2-MORPHOLIN-4-YL-2-OXOETHYL)PIPERIDIN-4-YL]METHYL}IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

Participants

Role	Name	HCID	Charge
Reactant	Morpholine, 4-(chloroacetyl)-	HCID 74040	—
Reactant	5-amino-6-chloro-2-ethyl-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyridine-8-carboxamide	HCID 9949612	—
Product	5-AMINO-6-CHLORO-2-ETHYL-N-{[1-(2-MORPHOLIN-4-YL-2-OXOETHYL)PIPERIDIN-4-YL]METHYL}IMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE	HCID 10050012	—

Reaction Steps

The title compound was prepared according to the procedure described in the step 5 of Example 4 from 5-amino-6-chloro-2-ethyl-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyridine-8-carboxamide (Example 4, Step 4) and 4-(chloroacetyl)morpholine (B. G. Hazra; V. S. Pore; S. P. Maybhate, Org. Prep. Proced. Int., 1989, 21, 355-8).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06951867B2
Source dataset	uspto-grants-2005_10
ORD ID	ord-3d6bcab2c20543699889dbf9a1d11eb8
Source note	uspto-grants-2005_10