4-Piperidinecarboxamide → 1-(2-Oxobutyl)piperidine-4-carboxamide

HRID 965807Notes

Reaction equation

[NH:1]1[CH2:9][CH2:8][CH:4]([C:5]([NH2:7])=[O:6])[CH2:3][CH2:2]1.Br[CH2:11][C:12](=[O:15])[CH2:13][CH3:14]>>[O:15]=[C:12]([CH2:13][CH3:14])[CH2:11][N:1]1[CH2:9][CH2:8][CH:4]([C:5]([NH2:7])=[O:6])[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 37724-Piperidinecarboxamide

HCID 131561-Bromo-2-butanone

Product 1

HCID 223132701-(2-Oxobutyl)piperidine-4-carboxamide

Procedure

The title compound was prepared according to the procedure described in the step 5 of Example 4 from isonipecotamide and 1-bromobutan-2-one.

Sources & evidence

ORD record: ord-55c400c36bf644be97379766cadd0219
Source dataset: uspto-grants-2005_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06951867B2

Reaction notes

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