5-Amino-6-chloro-2-ethylimidazo[1,2-a]pyridine-8-carboxylic acid → 5-amino-6-chloro-2-ethyl-N-{[1-(2-hydroxybutyl)piperidin-4-yl]methyl}-imidazo[1,2-a]pyridine-8-carboxamide

Participants

Reaction Steps

The tilte compound (free base) was prepared according to the procedure described in the step 5 of Example 1 from 5-amino-6-chloro-2-ethylimidazo[1,2-a]pyridine-8-carboxilic acid (Example 4, Step 2) and 1-[4-(aminomethyl)piperidin-1-yl]butan-2-ol (Example 13, Step 2).

Provenance & Evidence