Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 965812Generated: October 31, 2026

Isobutylene oxide → 5-AMINO-6-CHLORO-N-{[1-(2-HYDROXY-2-METHYLPROPYL)PIPERIDIN-4-YL]METHYL}-2-METHYLIMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDE

https://huagongshe.com/reaction/965812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutylene oxideHCID 11208—
ReactantHCID 11174673HCID 11174673—
Product5-AMINO-6-CHLORO-N-{[1-(2-HYDROXY-2-METHYLPROPYL)PIPERIDIN-4-YL]METHYL}-2-METHYLIMIDAZO[1,2-a]PYRIDINE-8-CARBOXAMIDEHCID 10046120—

Reaction Steps

The title compound was prepared according to the procedure described in Example 14 from 5-amino-6-chloro-2-methyl-N-(piperidin-4-ylmethyl)imidazo[1,2-a]pyridine-8-carboxamide (Example 15, Step 2) and 2,2-dimethyloxirane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06951867B2
Source datasetuspto-grants-2005_10
ORD IDord-543e7a8806244eaeb436419430142478
Source noteuspto-grants-2005_10