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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 966942Generated: October 31, 2026

Imidazole → (4-Aminobutoxy)(tert-butyl)dimethylsilane

https://huagongshe.com/reaction/966942

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
Reactant4-Amino-1-butanolHCID 25868—
Reactanttert-Butyldimethylsilyl chlorideHCID 28928—
Product(4-Aminobutoxy)(tert-butyl)dimethylsilaneHCID 10750686—

Reaction Steps

In a manner similar to that in Reference Example 1, 4-amino-1-butanol was reacted with tert-butyldimethylsilyl chloride in the presence of imidazole to give 4-(tert-butyldimethylsilyloxy)-1-butylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06953785B2
Source datasetuspto-grants-2005_10
ORD IDord-c7e68210966941f7972aff00b68a638f
Source noteuspto-grants-2005_10