反应详情

In analogy to the method described in example 1.2, 1.65 g (5.66 mmol) of trans-(4-hydroxymethyl-cyclohexylmethyl)-methyl-carbamic acid benzyl ester were treated with dimethylsulfoxide/triethylamine in dichloromethane between −78° C. and room temperature to yield 1.6 g (97.6%) trans-(4-formyl-cyclohexylmethyl)-methyl-carbamic acid benzyl ester as colorless oil, MS: 289 (M).