HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Prolinol → HCID 178484061, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Prolinol | HCID 640091 | — |
| Reactant | HCID 178484054 | HCID 178484054 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 178484061 | HCID 178484061 | — |
Reaction Steps
In analogy to the method described in example 12.1, trans-N-[4-(4-bromo-butoxymethyl)-cyclohexylmethyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide was reacted with (S)-2-hydroxymethyl-pyrrolidine in N,N-dimethylacetamide at room temperature to yield trans-N-{4-[4-((S)-2-hydroxymethyl-pyrrolidin-1-yl)-butoxymethyl]-cyclohexylmethyl}-N-methyl-4-trifluoromethyl-benzenesulfonamide as colorless solid, MS: 521 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06953806B2 |
| Source dataset | uspto-grants-2005_10 |
| ORD ID | ord-d5939c0585ef4da99e29f41e701f84db |
| Source note | uspto-grants-2005_10 |