Sodium ion → 2,5-Dichloro-3-fluoropyridine

HRID 96749Notes

Reaction equation

HRID 96749 reaction equation
[FH:1].[N:11]([O-:12])=[O:13].[NH2:2][c:3]1[c:4]([Cl:10])[n:5][cH:6][c:7]([Cl:9])[cH:8]1.[Na+:14]>>[F:1][c:3]1[c:4]([Cl:10])[n:5][cH:6][c:7]([Cl:9])[cH:8]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 946NitriteHCID 14917Hydrofluoric AcidHCID 27999993-Amino-2,5-dichloropyridine

Product 1

HCID 109648772,5-Dichloro-3-fluoropyridine

Sources & evidence

ORD record
ord-8eb600f8e8a04ad49d8d57d2ef7c2498
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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