反应详情

4N sodium hydroxide (6.8 mL) was added to an ethanol solution (30 mL) of the compound (2.2 g) obtained in Step 3 of Example 4 and the mixture was heated under reflux for four and half hours. The solvent was removed under reduced pressure and to the residue was added water (30 mL), and the precipitate was collected by filtration.

1. temperaturethe mixture was heated
2. temperatureunder reflux for four and half hours
3. customThe solvent was removed under reduced pressure and to the residue
4. additionwas added water (30 mL)
5. filtrationthe precipitate was collected by filtration