Hydrochloric Acid → HCID 69732702, compound

HRID 967788Notes

Reaction equation

HRID 967788 reaction equation
[OH:1][C:2]1([CH2:20][N:21]([CH3:31])[C:22]2[CH:30]=[CH:29][C:25]([C:26]([OH:28])=[O:27])=[CH:24][CH:23]=2)[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][C:10]2[CH:15]=[CH:14][C:13]([S:16]([CH3:19])(=[O:18])=[O:17])=[CH:12][CH:11]=2)[CH2:4][CH2:3]1.[ClH:32]>[OH-].[Na+]>[ClH:32].[OH:1][C:2]1([CH2:20][N:21]([CH3:31])[C:22]2[CH:23]=[CH:24][C:25]([C:26]([OH:28])=[O:27])=[CH:29][CH:30]=2)[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][C:10]2[CH:11]=[CH:12][C:13]([S:16]([CH3:19])(=[O:17])=[O:18])=[CH:14][CH:15]=2)[CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 10138547HCID 10138547, compound

Product 1

HCID 69732702HCID 69732702, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

The compound (0.65 g) obtained in Step 3 of Example 27 was dissolved in an aqueous 0.4N sodium hydroxide solution (25 mL) and the pH was adjusted to 3 to 4 by using 3N hydrochloric acid at 5° C. and the residue was stirred at the same temperature for thirty minutes. The precipitate was collected by filtration and washed with cold water, and dried under reduced pressure to obtain the titled compound (0.61 g) as crystals.

Workup

  1. customat 5° C.
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with cold water
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-c5ca034a41054eea8ceac8db1445d97b
Source dataset
uspto-grants-2005_10
Patent number
US06956046B2

Reaction notes

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