Bicarbonate Ion → 7-(5-(trifluoromethyl)pyridin-2-yl)-5,6,7,8-tetrahydro-N-(3-methoxyphenyl)pyrido[3,4-d]pyrimidin-4-amine
Reaction equation
[C:35](=[O:36])([OH:37])[O-:38].[CH3:22][O:23][c:24]1[cH:25][c:26]([NH2:27])[cH:28][cH:29][cH:30]1.[CH3:31][C:32]#[N:33].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][N:9]([c:12]1[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[CH2:10][CH2:11]2.[IH:34].[Na+:39]>>[c:2]1([NH:27][c:26]2[cH:25][c:24]([O:23][CH3:22])[cH:30][cH:29][cH:28]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[CH2:8][N:9]([c:12]1[n:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[CH2:10][CH2:11]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-81fabe270be449ee827ae550f153909f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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