Perfluoropropionyl fluoride → HCID 11476181, compound

HRID 968083Notes

Reaction equation

HRID 968083 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][CH:7]([CH2:9][OH:10])[CH3:8].[C:11]([C:15]([C:18](F)=[O:19])([F:17])[F:16])([F:14])([F:13])[F:12]>C([O-])(O)=O.[Na+]>[C:11]([C:15]([C:18]([O:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][CH:7]([CH2:9][O:10][C:18]([C:15]([C:11]([F:12])([F:13])[F:14])([F:16])[F:17])=[O:19])[CH3:8])=[O:19])([F:17])[F:16])([F:14])([F:13])[F:12]

Participants

4

Reactant 2

HCID 67912Perfluoropropionyl fluorideHCID 11435026HCID 11435026, compound

Product 1

HCID 11476181HCID 11476181, compound

Reagents, catalysts & solvents 1

HCID 516892Sodium BicarbonateSolvent

Conditions

Temperature
30 °C

Procedure

HO(CH2)4OCH(CH3)CH2OH (18.8 g) obtained in Example 2-3 was put into a round bottom flask and stirred while maintaining the internal temperature at 30° C. Together with nitrogen, CF3CF2COF (276 g) was supplied over 6 hours while maintaining the internal temperature at 30° C. After completion of the reaction, stirring was continued for 2 hours at an internal temperature of 30° C. while supplying nitrogen gas, whereupon a 5% NaHCO3 aqueous solution (300 ml) was added at an internal temperature of at most 15° C.

Workup

  1. temperaturewhile maintaining the internal temperature at 30° C
  2. customAfter completion of the reaction
  3. stirringstirring

Sources & evidence

ORD record
ord-551406ba06254553a4f70f2ea893c278
Source dataset
uspto-grants-2005_10
Patent number
US06956138B2

Reaction notes

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