Chloride → 6-amino-2,2-bisfluoromethyl-4-(2-pyridyl)-2H-1-benzopyran

HRID 96813Notes

Reaction equation

HRID 96813 reaction equation
[CH3:25][CH2:26][OH:27].[Cl-:24].[F:1][CH2:2][C:3]1([CH2:22][F:23])[O:4][c:5]2[c:6]([cH:15][c:16]([N+:19]([O-:20])=[O:21])[cH:17][cH:18]2)[C:7]([c:9]2[n:10][cH:11][cH:12][cH:13][cH:14]2)=[CH:8]1>>[F:1][CH2:2][C:3]1([CH2:22][F:23])[O:4][c:5]2[c:6]([cH:15][c:16]([NH2:19])[cH:17][cH:18]2)[C:7]([c:9]2[n:10][cH:11][cH:12][cH:13][cH:14]2)=[CH:8]1

Participants

4

Reactant 3

HCID 312ChlorideHCID 702EthanolHCID 218313462,2-bisfluoromethyl-6-nitro-4-(2-pyridyl)-2H-1-benzopyran

Product 1

HCID 218313636-amino-2,2-bisfluoromethyl-4-(2-pyridyl)-2H-1-benzopyran

Sources & evidence

ORD record
ord-1baebe6ed6694ad29d23edc6d95b4caa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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