Potassium hexafluorophosphate → 4-Methylphenylbenzylpiperidinium hexafluorophosphate

HRID 968171Notes

Reaction equation

HRID 968171 reaction equation
[Br-].[CH3:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]2([CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[F:22][P-:23]([F:28])([F:27])([F:26])([F:25])[F:24].[K+]>O>[F:22][P-:23]([F:28])([F:27])([F:26])([F:25])[F:24].[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([N+:9]2([CH2:15][C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]2)=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 23688904Potassium hexafluorophosphateHCID 865888244-Methylphenylbenzylpiperidinium bromide

Product 1

HCID 865888224-Methylphenylbenzylpiperidinium hexafluorophosphateYield 94,806.398%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

An aqueous solution prepared by dissolving 4-methylphenylbenzylpiperidinium bromide (13.85 g, 0.04 mmol) in 20 ml of deionized water was mixed with an aqueous solution prepared by dissolving potassium hexafluorophosphate (KPF6, 8.83 g, 0.048 mmol) in 30 ml of deionized water and the produced white solid was collected by filtration. The resulting white solid was washed with 300 ml of deionized water, subjected to filtration and dried to obtain 4-methylphenylbenzylpiperidinium hexafluorophosphate (15.6 g, yield: 95%).

Workup

  1. customAn aqueous solution prepared
  2. additionwas mixed with an aqueous solution
  3. customprepared
  4. filtrationthe produced white solid was collected by filtration
  5. washThe resulting white solid was washed with 300 ml of deionized water
  6. filtrationsubjected to filtration
  7. customdried

Sources & evidence

ORD record
ord-28054d37f62c49b6a7368c37bf47b260
Source dataset
uspto-grants-2005_10
Patent number
US06958205B2

Reaction notes

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