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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 968207Generated: October 29, 2026

Isoxazole, 4-(chloromethyl)-3,5-dimethyl- → (2R)-2-[[2-Amino-5-[[(3,5-dimethyl-4-isoxazolyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1-propanol

https://huagongshe.com/reaction/968207

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoxazole, 4-(chloromethyl)-3,5-dimethyl-HCID 88246—
ReactantHCID 178461804HCID 178461804—
Product(2R)-2-[[2-Amino-5-[[(3,5-dimethyl-4-isoxazolyl)methyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-1-propanolHCID 86759883—

Reaction Steps

The titled compound was prepared from the product of example 4, step (b), and 3,5-dimethyl-4-chloromethylisoxazole using the method of example 4, step (c) to give a white powder (0.016 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06958343B2
Source datasetuspto-grants-2005_10
ORD IDord-c1ee0c372ae340afb77ef8091a29a92c
Source noteuspto-grants-2005_10