HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → S-(2-Chloroethyl)cysteine--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Amino-3-(2-hydroxyethylsulfanyl)propanoic acid | HCID 4610750 | — |
| Product | S-(2-Chloroethyl)cysteine--hydrogen chloride (1/1) | HCID 24187093 | 75.4% |
Reaction Steps
33.9 g of 2-amino-3-(2-hydroxy-ethylsulfanyl)-propionic acid was dissolved in 800 mL of concentrated hydrogen chloride and the solution was stirred for 7 h to obtain a buff solid. The solid was recrystallized in isopropanol to obtain a white powder (34.2 g). Yield 75.4%, mp 185-186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07304057B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-a3566ba2ab3c4afca120512bc7db5aa6 |
| Source note | uspto-grants-2007_12 |