HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59015781, compound → HCID 59015784, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59015781 | HCID 59015781 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 59015784 | HCID 59015784 | — |
Reaction Steps
In a Parr apparatus, hydrogenate an ethanolic solution of 3-nitro-2′-trifluoromethyl-biphenyl-4-carboxylic acid methyl ester (5.54 g, 0.0169 mol) under 55 psi of hydrogen using tetrakis(triphenylphosphine)palladium (0) (300 mg). After 18 hours, filter the mixture through celite and concentrate under reduced pressure to give 3-amino-2′-trifluoromethyl-biphenyl-4-carboxylic acid methyl ester as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07304059B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-593e06b6179546af9368ef5b87b54aa3 |
| Source note | uspto-grants-2007_12 |