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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 968581Generated: October 29, 2026

2-Acetylamino-4-(3-trifluoromethyl-pyridin-2-yl)-benzamide → HCID 178433407, compound

https://huagongshe.com/reaction/968581

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Acetylamino-4-(3-trifluoromethyl-pyridin-2-yl)-benzamideHCID 22030471—
SolventSodium HydroxideHCID 14798—
ProductHCID 178433407HCID 178433407—

Reaction Steps

Suspend 2-acetylamino-4-(3-trifluoromethyl-pyridin-2-yl)-benzamide in 20 ml of 20% NaOH, stir for 30 minutes at room temperature. Filter, acidify to pH=6, extract with EtOAc, and concentrate under vacuum to give 2-methyl-7-(3-trifluoromethyl-pyridin-2-yl)-quinazolin-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07304059B2
Source datasetuspto-grants-2007_12
ORD IDord-39340a5ce0cd49718b3616297db0aac2
Source noteuspto-grants-2007_12