Iodoethane → HCID 131726703, compound

Participants

Reaction Steps

(R)-1-{[1-(Cyclopentylmethyl)-7-methoxy-1H-indol-3-yl]carbonyl}-4-ethyl-3-methylpiperazine, hydrochloride salt was prepared using (R)-1-{[1-(cyclopentylmethyl)-7-methoxy-1H-indol-3-yl]carbonyl}-3-methylpiperazine (prepared as detailed in example 12) and iodoethane. 1H NMR (400 MHz, CD3OD) δH 1.24-1.42 (8H, m), 1.51-1.73 (6H, m), 2.43 (1H, heptet, J 7.6), 3.12-3.23 (2H, m), 3.47-3.71 (5H, br m), 3.95 (3H, s), 4.38 (2H, d, J 6.9), 4.51 (2H, br s), 6.77 (1H, d, J 8.2), 7.10 (1H, t, J 7.7), 7.26 (1H, d, J 8.1), 7.60 (1H, s). EIMS; m/z=384.2 [M+H]+.

Provenance & Evidence