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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 96871Generated: October 28, 2026

1,2-Dichloroethane → Tert-butyl 4-[tert-butyl(dimethyl)silyl]oxy-2-[[[2-chloro-4-(4-methoxyphenoxy)pyrimidin-5-yl]amino]methyl]pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/96871

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAcetic AcidHCID 176—
ReactantDichloromethaneHCID 6344—
Reactant1-Tert-butoxycarbonyl-4-tert-butyldimethylsilyloxy-2-formylpyrrolidineHCID 14863943—
ReactantHCID 58243054HCID 58243054—
ProductTert-butyl 4-[tert-butyl(dimethyl)silyl]oxy-2-[[[2-chloro-4-(4-methoxyphenoxy)pyrimidin-5-yl]amino]methyl]pyrrolidine-1-carboxylateHCID 87305967—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-474af3b35e964390bc5497c3844afc8b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)