HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → Diisopropylethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | Diisopropylethylamine | HCID 81531 | — |
Reaction Steps
By reacting compound (XIIIB) obtained in Step 9B with compound (XVIIIB) in chloroform, methylene chloride, tetrahydrofuran, toluene, ethyl acetate, or a mixed solvent thereof, in the presence of a base such as pyridine, triethylamine, N,N-diisopropylethylamine and the like, compound (1-4) can be obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07304174B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-0fb7afe6f15e473e8a6f9095b9bd0fc7 |
| Source note | uspto-grants-2007_12 |