HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 969118Generated: October 31, 2026
tert-Butyl piperazine-1-carboxylate → HCID 69444013, compound
https://huagongshe.com/reaction/969118
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | Ethyl 1-(6-chloropyridin-3-yl)cyclopropanecarboxylate | HCID 86602273 | — |
| Product | HCID 69444013 | HCID 69444013 | — |
Reaction Steps
A mixture of ethyl 1-(6-chloropyridin-3-yl)cyclopropanecarboxylate (225.7 mg, 0.001000 mol) and tert-butyl piperazine-1-carboxylate (3.0 eq.) was heated at 130° C. for 6 h. After cooling, the mixture was flash chromatographed on a silica gel column to afford the desired product. LC/MS: 376.5 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07304081B2 |
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| Source dataset | uspto-grants-2007_12 |
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| ORD ID | ord-0bcb9f44aa6e4ad098ee676e1a86a7e6 |
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| Source note | uspto-grants-2007_12 |
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