反应详情

587 mg (2 mmol) 8-benzyloxy-5-oxiranyl-1H-quinolin-2-one and 358 mg (2 mmol) 2-(4-methoxy-phenyl)-1,1-dimethyl-ethylamine are stirred in 5 mL n-butanol for 6 hours at 140° C. Then the solvent is distilled off and the residue is purified by chromatography (reverse phase; water/acetonitrile gradient).

1. distillationThen the solvent is distilled off
2. customthe residue is purified by chromatography (reverse phase; water/acetonitrile gradient)