HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methoxyphenyl)-1,1-dimethylethylamine → HCID 69462583, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methoxyphenyl)-1,1-dimethylethylamine | HCID 91892 | — |
| Reactant | 8-(Benzyloxy)-5-(oxiran-2-yl)quinolin-2(1H)-one | HCID 13897641 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 69462583 | HCID 69462583 | — |
Reaction Steps
587 mg (2 mmol) 8-benzyloxy-5-oxiranyl-1H-quinolin-2-one and 358 mg (2 mmol) 2-(4-methoxy-phenyl)-1,1-dimethyl-ethylamine are stirred in 5 mL n-butanol for 6 hours at 140° C. Then the solvent is distilled off and the residue is purified by chromatography (reverse phase; water/acetonitrile gradient).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307076B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-a8eddcc46d5c4e5f830835763cf262fc |
| Source note | uspto-grants-2007_12 |