反应详情

10.1 g (26 mmol) 5-benzyloxy-8-(2-ethoxy-2-hydroxy-acetyl)-2,2-dimethyl-4H-benzo[1,4]oxazin-3-one and 4 g (22 mmol) 2-(4-methoxy-phenyl)-1,1-dimethyl-ethylamine are stirred in 100 ml of ethanol for 2 hours at 60 to 70° C. After some of the solvent has been distilled off a solid is precipitated out during cooling, and this is suction filtered and washed with ethanol and diethyl ether.

1. distillationAfter some of the solvent has been distilled off a solid
2. customis precipitated out
3. temperatureduring cooling
4. filtrationthis is suction filtered
5. washwashed with ethanol and diethyl ether