反应详情

tert-Butyl ((1R,3S)-3-isopropyl-3-{[7-(trifluoromethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclopentyl)carbamate (0.80 g, 1.76 mmol) was dissolved in a 4 M solution of HCl in 1,4-dioxane (10 mL). After being stirred for 2 hours, the solution was evaporated in vacuo to give the desired product (0.64 g, 94%) as an HCl salt. MS calculated for C19H25F3N2O: (M+H)+355; found 355.2.

1. customthe solution was evaporated in vacuo