HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 69510346, compound → HCID 69510665, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 69510346 | HCID 69510346 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 69510665 | HCID 69510665 | — |
Reaction Steps
2-Nitro-N-{4-[1-methyl-1-(1-methylpiperidin-4-yl)ethyl]phenyl}benzamide (Step A, 750 mg) was mixed with Pd/C (10%, 200 mg) in EtOH (80 mL) and hydrogenated under a hydrogen atmosphere for 1 h. The solution was filtered through Celite® and evaporated to give the amine used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307088B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-0cf36382da0a4803a0b6bb785fa0e214 |
| Source note | uspto-grants-2007_12 |