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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 969663Generated: October 30, 2026

HCID 69510346, compound → HCID 69510665, compound

https://huagongshe.com/reaction/969663

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69510346HCID 69510346—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 69510665HCID 69510665—

Reaction Steps

2-Nitro-N-{4-[1-methyl-1-(1-methylpiperidin-4-yl)ethyl]phenyl}benzamide (Step A, 750 mg) was mixed with Pd/C (10%, 200 mg) in EtOH (80 mL) and hydrogenated under a hydrogen atmosphere for 1 h. The solution was filtered through Celite® and evaporated to give the amine used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07307088B2
Source datasetuspto-grants-2007_12
ORD IDord-0cf36382da0a4803a0b6bb785fa0e214
Source noteuspto-grants-2007_12