HRID9697

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21986458

Ethyl (4-hydroxy-2-methylphenoxy)acetate

C11H14O4

2 次

HCID21986476

未命名化合物

2 次

结构：CCOC(=O)COc1ccc(SCc2coc(-c3ccc(C(F)(F)F)cc3)c2)cc1C

HCID21986477

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)COc1ccc(OCc2sc(-c3ccc(C(F)(F)F)c(F)c3F)cc2C)cc1C

HCID21986290

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by a method analogous to that used for the preparation of ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate (example 1) using ethyl(4-hydroxy-2-methylphenoxy)acetate (intermediate 7) and {5-[2,3-difluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol (intermediate 122).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-76587a1d5d874959b2ba87d99a8c3da7
来源数据集: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07091237B2
来源说明: uspto-grants-2006_08

反应 SMILES

C(OC(=O)COC1C=CC(SCC2C=C(C3C=CC(C(F)(F)F)=CC=3)OC=2)=CC=1C)C.[CH2:32]([O:34][C:35](=[O:46])[CH2:36][O:37][C:38]1[CH:43]=[CH:42][C:41]([OH:44])=[CH:40][C:39]=1[CH3:45])[CH3:33].[F:47][C:48]1[C:53]([F:54])=[C:52]([C:55]([F:58])([F:57])[F:56])[CH:51]=[CH:50][C:49]=1[C:59]1[S:63][C:62]([CH2:64]O)=[C:61]([CH3:66])[CH:60]=1>>[CH2:32]([O:34][C:35](=[O:46])[CH2:36][O:37][C:38]1[CH:43]=[CH:42][C:41]([O:44][CH2:64][C:62]2[S:63][C:59]([C:49]3[CH:50]=[CH:51][C:52]([C:55]([F:56])([F:57])[F:58])=[C:53]([F:54])[C:48]=3[F:47])=[CH:60][C:61]=2[CH3:66])=[CH:40][C:39]=1[CH3:45])[CH3:33]