HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59017453, compound → HCID 59017445, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59017453 | HCID 59017453 | — |
| Solvent | Isopropanol hexane | HCID 21585144 | — |
| Product | HCID 59017445 | HCID 59017445 | — |
Reaction Steps
N-(4,4-Dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-yl)-2-[1-(2-methylamino-pyrimidin-4-yl)-ethylamino]-benzamide (190 mg, 0.44 mmol) was separated on a chiral column (Chiralcel AD, 250×4.6 (mm) 10u, n-Hexane/i-PrOH/0.2% DEA (70:30), 1 mL/min). The (S) enantiomer was isolated. MS m/z: 431.3 (M+H). Calc'd. for C25H31N6O-431.55.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07307088B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-66061308318d4e179058d6fc116cbb0e |
| Source note | uspto-grants-2007_12 |