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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 969705Generated: October 29, 2026

HCID 59017453, compound → HCID 59017445, compound

https://huagongshe.com/reaction/969705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59017453HCID 59017453—
SolventIsopropanol hexaneHCID 21585144—
ProductHCID 59017445HCID 59017445—

Reaction Steps

N-(4,4-Dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-yl)-2-[1-(2-methylamino-pyrimidin-4-yl)-ethylamino]-benzamide (190 mg, 0.44 mmol) was separated on a chiral column (Chiralcel AD, 250×4.6 (mm) 10u, n-Hexane/i-PrOH/0.2% DEA (70:30), 1 mL/min). The (S) enantiomer was isolated. MS m/z: 431.3 (M+H). Calc'd. for C25H31N6O-431.55.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07307088B2
Source datasetuspto-grants-2007_12
ORD IDord-66061308318d4e179058d6fc116cbb0e
Source noteuspto-grants-2007_12