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HRID969750

反应详情

EQUATION

反应方程式

HRID 969750 的结构方程式

REACTANTS

反应物

2
反应SMILES：CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)ccc1F
HCID11347588

未命名化合物

2 次

反应SMILES：CC1Cn2c(nnc2C(F)(F)F)C(C)N1.Cl
HCID131726716

未命名化合物

PRODUCTS

产物

2
反应SMILES：Cl
HCID313

Hydrochloric Acid

ClH

反应SMILES：CC1Cn2c(nnc2C(F)(F)F)C(C)N1C(=O)C[C@H](N)Cc1cc(F)ccc1F.Cl
HCID131726715

未命名化合物

PROCEDURE

实验过程

The title compound is prepared by coupling 6,8-dimethyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine, hydrochloride from Example 8, Step C with (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,5-difluorophenyl)butanoic acid (Intermediate 1). Treatment of the coupled product with methanolic hydrogen chloride provides the title compound.

WORKUP

后处理

  1. customThe title compound is prepared