HuagongsheHuagongshe Chemistry Print Report · For research reference only
{5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol → Ethyl[4-({5-[2-fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)-2-methylphenoxy]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {5-[2-Fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol | HCID 21986424 | — |
| Reactant | Ethyl (4-hydroxy-2-methylphenoxy)acetate | HCID 21986458 | — |
| Reactant | Ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate | HCID 21986477 | — |
| Product | Ethyl[4-({5-[2-fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methoxy)-2-methylphenoxy]acetate | HCID 21986388 | — |
Reaction Steps
The title compound was prepared by a method analogous to that used for the preparation of ethyl{2-methyl-4-[({5-[4-(trifluoromethyl)phenyl]-3-furyl}methyl)thio]phenoxy}acetate (example 1) using ethyl(4-hydroxy-2-methylphenoxy)acetate (intermediate 7) and {5-[2-fluoro-4-(trifluoromethyl)phenyl]-3-methylthien-2-yl}methanol (intermediate 124).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091237B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-a1c3917ecc264ee88309357cfcc15257 |
| Source note | uspto-grants-2006_08 |